Inhibition of extranodal NK/T-cell lymphoma by Chiauranib through an AIF-dependent pathway and its synergy with L-asparaginase

Extranodal NK/T-cell lymphoma (NKTL) is a rare and aggressive form of extranodal lymphoma with a poor prognosis. Currently, there are very limited treatment options for patients with advanced-stage disease or those with relapsed/recurrent disease. Here we show that Chiauranib, an orally small molecu...

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Detalles Bibliográficos
Autores principales: Gao, Tianxiao, Huang, Jieye, Yin, Haofan, Huang, Jiajia, Xie, Jinye, Zhou, Ti, Fan, Wei, Yang, Xia, Gao, Guoquan, Li, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169864/
https://www.ncbi.nlm.nih.gov/pubmed/37160920
http://dx.doi.org/10.1038/s41419-023-05833-w

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