A comprehensive regulatory and industry review of modeling and simulation practices in oncology clinical drug development

Exposure–response (E–R) analyses are an integral component in the development of oncology products. Characterizing the relationship between drug exposure metrics and response allows the sponsor to use modeling and simulation to address both internal and external drug development questions (e.g., opt...

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Detalles Bibliográficos
Autores principales: Ruiz-Garcia, Ana, Baverel, Paul, Bottino, Dean, Dolton, Michael, Feng, Yan, González-García, Ignacio, Kim, Jaeyeon, Robey, Seth, Singh, Indrajeet, Turner, David, Wu, Shu-Pei, Yin, Donghua, Zhou, Di, Zhu, Hao, Bonate, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169901/
https://www.ncbi.nlm.nih.gov/pubmed/36870005
http://dx.doi.org/10.1007/s10928-023-09850-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169901/
https://www.ncbi.nlm.nih.gov/pubmed/36870005
http://dx.doi.org/10.1007/s10928-023-09850-2

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