Cargando…
A comprehensive regulatory and industry review of modeling and simulation practices in oncology clinical drug development
Exposure–response (E–R) analyses are an integral component in the development of oncology products. Characterizing the relationship between drug exposure metrics and response allows the sponsor to use modeling and simulation to address both internal and external drug development questions (e.g., opt...
| Autores principales: | , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169901/ https://www.ncbi.nlm.nih.gov/pubmed/36870005 http://dx.doi.org/10.1007/s10928-023-09850-2 |