Cargando…

Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common form of dementia, with cerebrospinal fluid (CSF) β-amyloid (Aβ), total Tau, and phosphorylated Tau (pTau) providing the most sensitive and specific biomarkers for diagnosis. However, these diagnostic biomarkers do not reflect the complex changes in AD brai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watson, Caroline M., Dammer, Eric B., Ping, Lingyan, Duong, Duc M., Modeste, Erica, Carter, E. Kathleen, Johnson, Erik C. B., Levey, Allan I., Lah, James J., Roberts, Blaine R., Seyfried, Nicholas T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Data Descriptor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170100/ https://www.ncbi.nlm.nih.gov/pubmed/37160957 http://dx.doi.org/10.1038/s41597-023-02158-3

Ejemplares similares

Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer’s disease
por: Modeste, Erica S., et al.
Publicado: (2023)

Multi-platform proteomic analysis of Alzheimer’s disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome
por: Dammer, Eric B., et al.
Publicado: (2022)

Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease
por: Ping, Lingyan, et al.
Publicado: (2018)

Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer’s disease
por: Zhou, Maotian, et al.
Publicado: (2020)

Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer’s disease
por: Ping, Lingyan, et al.
Publicado: (2020)

Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer’s Disease
por: Higginbotham, Lenora, et al.
Publicado: (2019)

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease
por: Higginbotham, Lenora, et al.
Publicado: (2020)

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease
por: Wang, Minghui, et al.
Publicado: (2018)

Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease
por: Donovan, Laura E, et al.
Publicado: (2013)

Correction to: Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer’s disease
por: Donovan, Laura E., et al.
Publicado: (2021)

Proteomic Network Analysis of Alzheimer’s Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE ε4 Genotype and Atomoxetine Treatment
por: Dammer, Eric B., et al.
Publicado: (2023)

Protein interactors of 3-O sulfated heparan sulfates in human MCI and age-matched control cerebrospinal fluid
por: Ferreira, Andreia, et al.
Publicado: (2023)

Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease
por: Dai, Jingting, et al.
Publicado: (2018)

Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
por: Johnson, Erik C. B., et al.
Publicado: (2023)

Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease
por: Johnson, Erik C. B., et al.
Publicado: (2018)

Differential Phagocytic Properties of CD45(low) Microglia and CD45(high) Brain Mononuclear Phagocytes—Activation and Age-Related Effects
por: Rangaraju, Srikant, et al.
Publicado: (2018)

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease
por: Rangaraju, Srikant, et al.
Publicado: (2018)

A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain
por: Umoh, Mfon E, et al.
Publicado: (2017)

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer’s disease due to autosomal dominant genetic mutations and trisomy 21
por: Hales, Chadwick M, et al.
Publicado: (2014)

The 2021 update of the EPA’s adverse outcome pathway database
por: Mortensen, Holly M., et al.
Publicado: (2021)

Inter-laboratory mass spectrometry dataset based on passive sampling of drinking water for non-target analysis
por: Schulze, Bastian, et al.
Publicado: (2021)

An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia
por: Provez, Lien, et al.
Publicado: (2022)

Mass spectrometry quantitation of proteins from small pools of developing auditory and vestibular cells
por: Krey, Jocelyn F., et al.
Publicado: (2018)

Comprehensive high-resolution multiple-reaction monitoring mass spectrometry for targeted eicosanoid assays
por: Sorgi, Carlos Artério, et al.
Publicado: (2018)

Comprehensive draft of the mouse embryonic fibroblast lysosomal proteome by mass spectrometry based proteomics
por: Ponnaiyan, Srigayatri, et al.
Publicado: (2020)

Identification of Conserved Proteomic Networks in Neurodegenerative Dementia
por: Swarup, Vivek, et al.
Publicado: (2020)

Temporally inter-comparable maps of terrestrial wilderness and the Last of the Wild
por: Allan, James R., et al.
Publicado: (2017)

Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer’s disease-related proteins
por: Rangaraju, Srikant, et al.
Publicado: (2018)

Direct infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control
por: Kirwan, Jennifer A, et al.
Publicado: (2014)

Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research
por: Fox Ramos, Alexander E., et al.
Publicado: (2019)

Mass spectrometry data on specialized metabolome of medicinal plants used in East Asian traditional medicine
por: Kang, Kyo Bin, et al.
Publicado: (2022)

CT-ORG, a new dataset for multiple organ segmentation in computed tomography
por: Rister, Blaine, et al.
Publicado: (2020)

Coaggregation of RNA-Binding Proteins in a Model of TDP-43 Proteinopathy with Selective RGG Motif Methylation and a Role for RRM1 Ubiquitination
por: Dammer, Eric B., et al.
Publicado: (2012)

Helium, inorganic and organic carbon isotopes of fluids and gases across the Costa Rica convergent margin
por: Barry, Peter H., et al.
Publicado: (2019)

Metagenome sequencing and 98 microbial genomes from Juan de Fuca Ridge flank subsurface fluids
por: Jungbluth, Sean P., et al.
Publicado: (2017)

Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer’s Disease
por: Guo, Qi, et al.
Publicado: (2021)

Genotoype-by-sequencing of three geographically distinct populations of Olympia oysters, Ostrea lurida
por: White, Samuel J., et al.
Publicado: (2017)

A quantum chemical molecular dynamics repository of solvated ions
por: Gregory, Kasimir P., et al.
Publicado: (2022)

A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation
por: Rangaraju, Srikant, et al.
Publicado: (2017)

TBK1 interacts with tau and enhances neurodegeneration in tauopathy
por: Abreha, Measho H., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7tqb4tjtdn1dpcdbivfk5ht1uh