Atomistic Picture of Opening–Closing Dynamics of DNA Holliday Junction Obtained by Molecular Simulations

[Image: see text] Holliday junction (HJ) is a noncanonical four-way DNA structure with a prominent role in DNA repair, recombination, and DNA nanotechnology. By rearranging its four arms, HJ can adopt either closed or open state. With enzymes typically recognizing only a single state, acquiring deta...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengyue, Šponer, Jiří, Bussi, Giovanni, Mlýnský, Vojtěch, Šulc, Petr, Simmons, Chad R., Stephanopoulos, Nicholas, Krepl, Miroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170514/
https://www.ncbi.nlm.nih.gov/pubmed/37126365
http://dx.doi.org/10.1021/acs.jcim.3c00358

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