A monoadduct generating Ru(ii) complex induces ribosome biogenesis stress and is a molecular mimic of phenanthriplatin

Ruthenium complexes are often investigated as potential replacements for platinum-based chemotherapeutics in hopes of identifying systems with improved tolerability in vivo and reduced susceptibility to cellular resistance mechanisms. Inspired by phenanthriplatin, a non-traditional platinum agent th...

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Detalles Bibliográficos
Autores principales: Mitchell, Richard J., Kriger, Sarah M., Fenton, Alexander D., Havrylyuk, Dmytro, Pandeya, Ankit, Sun, Yang, Smith, Tami, DeRouchey, Jason E., Unrine, Jason M., Oza, Viral, Blackburn, Jessica S., Wei, Yinan, Heidary, David K., Glazer, Edith C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170627/
https://www.ncbi.nlm.nih.gov/pubmed/37181632
http://dx.doi.org/10.1039/d2cb00247g

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