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Influence of social and meteorological factors on hand, foot, and mouth disease in Sichuan Province

BACKGROUND: Hand, foot and mouth disease (HFMD) caused by a variety of enteroviruses remains a major public health problem in China. Previous studies have found that social factors may contribute to the inconsistency of the relationship patterns between meteorological factors and HFMD, but the concl...

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Autores principales: Jiang, Xiaohong, Ma, Yue, Lv, Qiang, Liu, Yaqiong, Zhang, Tao, Yin, Fei, Shui, Tiejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170695/
https://www.ncbi.nlm.nih.gov/pubmed/37165358
http://dx.doi.org/10.1186/s12889-023-15699-4
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author Jiang, Xiaohong
Ma, Yue
Lv, Qiang
Liu, Yaqiong
Zhang, Tao
Yin, Fei
Shui, Tiejun
author_facet Jiang, Xiaohong
Ma, Yue
Lv, Qiang
Liu, Yaqiong
Zhang, Tao
Yin, Fei
Shui, Tiejun
author_sort Jiang, Xiaohong
collection PubMed
description BACKGROUND: Hand, foot and mouth disease (HFMD) caused by a variety of enteroviruses remains a major public health problem in China. Previous studies have found that social factors may contribute to the inconsistency of the relationship patterns between meteorological factors and HFMD, but the conclusions are inconsistent. The influence of social factors on the association between meteorology and HFMD is still less well understood. We aimed to analyze whether social factors affected the effect of meteorological factors on HFMD in Sichuan Province. METHOD: We collected daily data on HFMD, meteorological factors and social factors in Sichuan Province from 2011 to 2017. First, we used a Bayesian spatiotemporal model combined with a distributed lag nonlinear model to evaluate the exposure-lag-response association between meteorological factors and HFMD. Second, by constructing the interaction of meteorological factors and social factors in the above model, the changes in the relative risk (RR) under different levels of social factors were evaluated. RESULTS: The cumulative exposure curves for average temperature, relative humidity, and HFMD were shaped like an inverted “V” and a “U” shape. As the average temperature increased, the RR increased and peaked at 19 °C (RR 1.020 [95% confidence interval CI 1.004–1.050]). The urbanization rate, per capita gross domestic product (GDP), population density, birth rate, number of beds in health care centers and number of kindergartens interacted with relative humidity. With the increase in social factors, the correlation curve between relative humidity and HFMD changed from an “S” shape to a “U” shape. CONCLUSIONS: Relative humidity and average temperature increased the risk of HFMD within a certain range, and social factors enhanced the impact of high relative humidity. These results could provide insights into the combined role of environmental factors in HFMD and useful information for regional interventions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-15699-4.
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spelling pubmed-101706952023-05-11 Influence of social and meteorological factors on hand, foot, and mouth disease in Sichuan Province Jiang, Xiaohong Ma, Yue Lv, Qiang Liu, Yaqiong Zhang, Tao Yin, Fei Shui, Tiejun BMC Public Health Research BACKGROUND: Hand, foot and mouth disease (HFMD) caused by a variety of enteroviruses remains a major public health problem in China. Previous studies have found that social factors may contribute to the inconsistency of the relationship patterns between meteorological factors and HFMD, but the conclusions are inconsistent. The influence of social factors on the association between meteorology and HFMD is still less well understood. We aimed to analyze whether social factors affected the effect of meteorological factors on HFMD in Sichuan Province. METHOD: We collected daily data on HFMD, meteorological factors and social factors in Sichuan Province from 2011 to 2017. First, we used a Bayesian spatiotemporal model combined with a distributed lag nonlinear model to evaluate the exposure-lag-response association between meteorological factors and HFMD. Second, by constructing the interaction of meteorological factors and social factors in the above model, the changes in the relative risk (RR) under different levels of social factors were evaluated. RESULTS: The cumulative exposure curves for average temperature, relative humidity, and HFMD were shaped like an inverted “V” and a “U” shape. As the average temperature increased, the RR increased and peaked at 19 °C (RR 1.020 [95% confidence interval CI 1.004–1.050]). The urbanization rate, per capita gross domestic product (GDP), population density, birth rate, number of beds in health care centers and number of kindergartens interacted with relative humidity. With the increase in social factors, the correlation curve between relative humidity and HFMD changed from an “S” shape to a “U” shape. CONCLUSIONS: Relative humidity and average temperature increased the risk of HFMD within a certain range, and social factors enhanced the impact of high relative humidity. These results could provide insights into the combined role of environmental factors in HFMD and useful information for regional interventions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-15699-4. BioMed Central 2023-05-10 /pmc/articles/PMC10170695/ /pubmed/37165358 http://dx.doi.org/10.1186/s12889-023-15699-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Jiang, Xiaohong
Ma, Yue
Lv, Qiang
Liu, Yaqiong
Zhang, Tao
Yin, Fei
Shui, Tiejun
Influence of social and meteorological factors on hand, foot, and mouth disease in Sichuan Province
title Influence of social and meteorological factors on hand, foot, and mouth disease in Sichuan Province
title_full Influence of social and meteorological factors on hand, foot, and mouth disease in Sichuan Province
title_fullStr Influence of social and meteorological factors on hand, foot, and mouth disease in Sichuan Province
title_full_unstemmed Influence of social and meteorological factors on hand, foot, and mouth disease in Sichuan Province
title_short Influence of social and meteorological factors on hand, foot, and mouth disease in Sichuan Province
title_sort influence of social and meteorological factors on hand, foot, and mouth disease in sichuan province
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170695/
https://www.ncbi.nlm.nih.gov/pubmed/37165358
http://dx.doi.org/10.1186/s12889-023-15699-4
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