Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of the femoral head by regulating miR-200b-3p-mediated Wnt/β-catenin signaling pathway via inhibiting SP1 expression: Astragalus polysaccharide regulates SONFH via SP1

BACKGROUND: Steroid-induced osteonecrosis of the femoral head (SONFH) is the necrosis of the femur bone caused by prolonged and massive use of corticosteroids. The present study probed into the significance of Astragalus polysaccharide (APS) in SONFH progression. METHODS: SONFH cell model was constr...

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Detalles Bibliográficos
Autores principales: Zhang, Shenyao, Dong, Kefang, Zeng, Xiangjing, Wang, Fan, Lu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170750/
https://www.ncbi.nlm.nih.gov/pubmed/37165386
http://dx.doi.org/10.1186/s12891-023-06447-1

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