Regulating lactate-related immunometabolism and EMT reversal for colorectal cancer liver metastases using shikonin targeted delivery

BACKGROUND: There are few effective medications for treating colorectal cancer and liver metastases (CRLM). The interactions among glycolysis, epithelial-mesenchymal transition (EMT), and immune microenvironment contribute to the progression of CRLM. A main glycolytic enzyme pyruvate Kinase M2 (PKM2...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Li, Xiong, Wei, Lin, Fenwang, Hou, Jiazhen, Chen, Guihua, Peng, Taoxing, He, Yihao, Wang, Rui, Xu, Qin, Huang, Yongzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170793/
https://www.ncbi.nlm.nih.gov/pubmed/37161591
http://dx.doi.org/10.1186/s13046-023-02688-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170793/
https://www.ncbi.nlm.nih.gov/pubmed/37161591
http://dx.doi.org/10.1186/s13046-023-02688-z

Ejemplares similares