Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

BACKGROUND: The Human Leukocyte Antigen (HLA) genes are a group of highly polymorphic genes that are located in the Major Histocompatibility Complex (MHC) region on chromosome 6. The HLA genotype affects the presentability of tumour antigens to the immune system. While knowledge of these genotypes i...

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Detalles Bibliográficos
Autores principales: Claeys, Arne, Merseburger, Peter, Staut, Jasper, Marchal, Kathleen, Van den Eynden, Jimmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170851/
https://www.ncbi.nlm.nih.gov/pubmed/37161318
http://dx.doi.org/10.1186/s12864-023-09351-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170851/
https://www.ncbi.nlm.nih.gov/pubmed/37161318
http://dx.doi.org/10.1186/s12864-023-09351-z

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