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Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data
BACKGROUND: The Human Leukocyte Antigen (HLA) genes are a group of highly polymorphic genes that are located in the Major Histocompatibility Complex (MHC) region on chromosome 6. The HLA genotype affects the presentability of tumour antigens to the immune system. While knowledge of these genotypes i...
Autores principales: | Claeys, Arne, Merseburger, Peter, Staut, Jasper, Marchal, Kathleen, Van den Eynden, Jimmy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170851/ https://www.ncbi.nlm.nih.gov/pubmed/37161318 http://dx.doi.org/10.1186/s12864-023-09351-z |
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