Cargando…

A fully automated micro‑CT deep learning approach for precision preclinical investigation of lung fibrosis progression and response to therapy

Micro-computed tomography (µCT)-based imaging plays a key role in monitoring disease progression and response to candidate drugs in various animal models of human disease, but manual image processing is still highly time-consuming and prone to operator bias. Focusing on an established mouse model of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buccardi, Martina, Ferrini, Erica, Pennati, Francesca, Vincenzi, Elena, Ledda, Roberta Eufrasia, Grandi, Andrea, Buseghin, Davide, Villetti, Gino, Sverzellati, Nicola, Aliverti, Andrea, Stellari, Franco Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170869/ https://www.ncbi.nlm.nih.gov/pubmed/37161569 http://dx.doi.org/10.1186/s12931-023-02432-3

Ejemplares similares

Micro-CT-derived ventilation biomarkers for the longitudinal assessment of pathology and response to therapy in a mouse model of lung fibrosis
por: Pennati, Francesca, et al.
Publicado: (2023)

A fully automated deep learning pipeline for micro-CT-imaging-based densitometry of lung fibrosis murine models
por: Vincenzi, Elena, et al.
Publicado: (2022)

Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening
por: Khalajzeyqami, Zahra, et al.
Publicado: (2022)

SSC-ILD mouse model induced by osmotic minipump delivered bleomycin: effect of Nintedanib
por: Ravanetti, Francesca, et al.
Publicado: (2021)

In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach
por: Mecozzi, Laura, et al.
Publicado: (2020)

The importance of routine quality control for reproducible pulmonary measurements by in vivo micro-CT
por: Mambrini, Martina, et al.
Publicado: (2022)

Indocyanine-enhanced mouse model of bleomycin-induced lung fibrosis with hallmarks of progressive emphysema
por: Grandi, Andrea, et al.
Publicado: (2023)

Imaging in non-cystic fibrosis bronchiectasis and current limitations
por: Ledda, Roberta Eufrasia, et al.
Publicado: (2021)

Fully automated calcium scoring predicts all-cause mortality at 12 years in the MILD lung cancer screening trial
por: Sabia, Federica, et al.
Publicado: (2023)

Persistency of Mesenchymal Stromal/Stem Cells in Lungs
por: Ferrini, Erica, et al.
Publicado: (2021)

Interstitial lung abnormalities: new insights between theory and clinical practice
por: Ledda, Roberta Eufrasia, et al.
Publicado: (2022)

Proteomic Fingerprint of Lung Fibrosis Progression and Response to Therapy in Bleomycin-Induced Mouse Model
por: Principi, Lucrezia, et al.
Publicado: (2023)

Volumetric Measurements in Lung Cancer Screening Reduces Unnecessary Low-Dose Computed Tomography Scans: Results from a Single-Center Prospective Trial on 4119 Subjects
por: Milanese, Gianluca, et al.
Publicado: (2022)

The role of the radiologist in diagnosing the COVID-19 infection. Parma experiences
por: Balbi, Maurizio, et al.
Publicado: (2020)

Frequency and characterization of ancillary chest CT findings in COVID-19 pneumonia
por: Silva, Mario, et al.
Publicado: (2021)

The diagnostic value of grey-scale inversion technique in chest radiography
por: Ledda, Roberta Eufrasia, et al.
Publicado: (2022)

Quantification of Lung Fibrosis in IPF-Like Mouse Model and Pharmacological Response to Treatment by Micro-Computed Tomography
por: Ruscitti, Francesca, et al.
Publicado: (2020)

Modeling pulmonary fibrosis through bleomycin delivered by osmotic minipump: a new histomorphometric method of evaluation
por: Ravanetti, Francesca, et al.
Publicado: (2020)

Concurrent pulmonary embolism in female monozygotic twins affected by Dercum’s disease
por: Ledda, Roberta Eufrasia, et al.
Publicado: (2019)

In Vivo Imaging of Transiently Transgenized Mice with a Bovine Interleukin 8 (CXCL8) Promoter/Luciferase Reporter Construct
por: Stellari, Fabio Franco, et al.
Publicado: (2012)

Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice
por: Stellari, Fabio Franco, et al.
Publicado: (2017)

Feasibility and Safety of Lung Cancer Screening and Prevention Program During the COVID-19 Pandemic
por: Milanese, Gianluca, et al.
Publicado: (2021)

Monitoring inflammation and airway remodeling by fluorescence molecular tomography in a chronic asthma model
por: Stellari, Fabio, et al.
Publicado: (2015)

Fully Automated Computational Approach for Precisely Measuring Organelle Acidification with Optical pH Sensors
por: Chandra, Anil, et al.
Publicado: (2022)

Machine learning predicts lung recruitment in acute respiratory distress syndrome using single lung CT scan
por: Pennati, Francesca, et al.
Publicado: (2023)

CHF6001 Inhibits NF-κB Activation and Neutrophilic Recruitment in LPS-Induced Lung Inflammation in Mice
por: Stellari, Fabio F., et al.
Publicado: (2019)

Non-Invasive Respiratory Assessment in Duchenne Muscular Dystrophy: From Clinical Research to Outcome Measures
por: Pennati, Francesca, et al.
Publicado: (2021)

Enlightened Mannhemia haemolytica lung inflammation in bovinized mice
por: Stellari, Fabio Franco, et al.
Publicado: (2014)

A Low-Dose CT-Based Radiomic Model to Improve Characterization and Screening Recall Intervals of Indeterminate Prevalent Pulmonary Nodules
por: Rundo, Leonardo, et al.
Publicado: (2021)

A New Challenge for Radiologists: Radiomics in Breast Cancer
por: Crivelli, Paola, et al.
Publicado: (2018)

Automated Coronary Artery Calcium and Quantitative Emphysema in Lung Cancer Screening: Association With Mortality, Lung Cancer Incidence, and Airflow Obstruction
por: Balbi, Maurizio, et al.
Publicado: (2023)

Alfaxalone and Dexmedetomidine as an Alternative to Gas Anesthesia for Micro-CT Lung Imaging in a Bleomycin-Induced Pulmonary Fibrosis Murine Model
por: Ferrini, Erica, et al.
Publicado: (2020)

Simulation of bronchial airway acoustics in healthy and asthmatic subjects
por: Aliboni, Lorenzo, et al.
Publicado: (2020)

Computational fluid dynamics of the airways after left‐upper pulmonary lobectomy: A case study
por: Tullio, Marta, et al.
Publicado: (2021)

Deep-learning-based precise characterization of microwave transistors using fully-automated regression surrogates
por: Calik, Nurullah, et al.
Publicado: (2023)

In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin
por: Stellari, Fabio, et al.
Publicado: (2015)

Screen-detected solid nodules: from detection of nodule to structured reporting
por: Silva, Mario, et al.
Publicado: (2021)

Changes in electromyographic activity, mechanical power, and relaxation rates following inspiratory ribcage muscle fatigue
por: Sarmento, Antonio, et al.
Publicado: (2021)

Erdheim-Chester disease presenting with cough, abdominal pain, and headache
por: Crivelli, Paola, et al.
Publicado: (2020)

Fully integrated, fully automated generation of short tandem repeat profiles
por: Tan, Eugene, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_j5dslc5oude83233orgcem3kal