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Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients
AIM: To explore the relationship between the serum sodium level on admission and all‐cause mortality in HF patients. DESIGN: A single‐center retrospective cohort study. METHODS: Patients hospitalized with HF at the Heart Failure Center, Fuwai Hospital, from November 2008 to November 2018 were enroll...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170941/ https://www.ncbi.nlm.nih.gov/pubmed/36929057 http://dx.doi.org/10.1002/nop2.1638 |
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author | Zhao, Lang Zhao, Xuemei Zhuang, Xiaofeng Zhai, Mei Wang, Yunhong Huang, Yan Zhou, Qiong Tian, Pengchao Liang, Lin Huang, Boping Huang, Liyan Feng, Jiayu Zhang, Yuhui Zhang, Jian |
author_facet | Zhao, Lang Zhao, Xuemei Zhuang, Xiaofeng Zhai, Mei Wang, Yunhong Huang, Yan Zhou, Qiong Tian, Pengchao Liang, Lin Huang, Boping Huang, Liyan Feng, Jiayu Zhang, Yuhui Zhang, Jian |
author_sort | Zhao, Lang |
collection | PubMed |
description | AIM: To explore the relationship between the serum sodium level on admission and all‐cause mortality in HF patients. DESIGN: A single‐center retrospective cohort study. METHODS: Patients hospitalized with HF at the Heart Failure Center, Fuwai Hospital, from November 2008 to November 2018 were enrolled. RESULTS: A total of 3649 patients were included, and the mean sodium level was 137.19 ± 4.36 mmol/L, with a range from 115.6 to 160.9 mmol/L. During a median follow‐up of 1101 days, mortality occurred in 1413 (38.7%) hospital survivors. After adjustment for age, sex, and other potential confounders, patients with sodium levels <135 mmol/L (hazard ratio [HR]: 1.67; 95% confidence interval [CI]: 1.29–2.16) and 135–137 mmol/L (HR: 1.34; 95% CI: 1.01–1.78) had an increased risk of all‐cause mortality compared to those with sodium levels of 139–141 mmol/L. |
format | Online Article Text |
id | pubmed-10170941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101709412023-05-11 Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients Zhao, Lang Zhao, Xuemei Zhuang, Xiaofeng Zhai, Mei Wang, Yunhong Huang, Yan Zhou, Qiong Tian, Pengchao Liang, Lin Huang, Boping Huang, Liyan Feng, Jiayu Zhang, Yuhui Zhang, Jian Nurs Open Research Articles AIM: To explore the relationship between the serum sodium level on admission and all‐cause mortality in HF patients. DESIGN: A single‐center retrospective cohort study. METHODS: Patients hospitalized with HF at the Heart Failure Center, Fuwai Hospital, from November 2008 to November 2018 were enrolled. RESULTS: A total of 3649 patients were included, and the mean sodium level was 137.19 ± 4.36 mmol/L, with a range from 115.6 to 160.9 mmol/L. During a median follow‐up of 1101 days, mortality occurred in 1413 (38.7%) hospital survivors. After adjustment for age, sex, and other potential confounders, patients with sodium levels <135 mmol/L (hazard ratio [HR]: 1.67; 95% confidence interval [CI]: 1.29–2.16) and 135–137 mmol/L (HR: 1.34; 95% CI: 1.01–1.78) had an increased risk of all‐cause mortality compared to those with sodium levels of 139–141 mmol/L. John Wiley and Sons Inc. 2023-03-16 /pmc/articles/PMC10170941/ /pubmed/36929057 http://dx.doi.org/10.1002/nop2.1638 Text en © 2023 The Authors. Nursing Open published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Research Articles Zhao, Lang Zhao, Xuemei Zhuang, Xiaofeng Zhai, Mei Wang, Yunhong Huang, Yan Zhou, Qiong Tian, Pengchao Liang, Lin Huang, Boping Huang, Liyan Feng, Jiayu Zhang, Yuhui Zhang, Jian Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients |
title | Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients |
title_full | Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients |
title_fullStr | Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients |
title_full_unstemmed | Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients |
title_short | Hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients |
title_sort | hyponatremia and lower normal serum sodium levels are associated with an increased risk of all‐cause death in heart failure patients |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170941/ https://www.ncbi.nlm.nih.gov/pubmed/36929057 http://dx.doi.org/10.1002/nop2.1638 |
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