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Isoamphipathic antibacterial molecules regulating activity and toxicity through positional isomerism

Peptidomimetic antimicrobials exhibit a selective interaction with bacterial cells over mammalian cells once they have achieved an optimum amphiphilic balance (hydrophobicity/hydrophilicity) in the molecular architecture. To date, hydrophobicity and cationic charge have been considered the crucial p...

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Detalles Bibliográficos
Autores principales: Barman, Swagatam, Mukherjee, Sudip, Jolly, Logia, Troiano, Cassandra, Grottesi, Alessandro, Basak, Debajyoti, Calligari, Paolo, Bhattacharjee, Brinta, Bocchinfuso, Gianfranco, Stella, Lorenzo, Haldar, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171078/
https://www.ncbi.nlm.nih.gov/pubmed/37181778
http://dx.doi.org/10.1039/d2sc06065e