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(1S,2S)-2-[(S)-2,2,2-Trifluoro-1-hydroxyethyl]-1-tetralol
The crystal structure of the title enantiopure tetralol derivative {systematic name: (1S,2S)-2-[(S)-2,2,2-trifluoro-1-hydroxyethyl]-1,2,3,4-tetrahydronaphthalen-1-ol}, C(12)H(13)F(3)O(2), synthesized by asymmetric transfer hydrogenation, was elucidated by low-temperature single-crystal X-ray...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171325/ https://www.ncbi.nlm.nih.gov/pubmed/37180347 http://dx.doi.org/10.1107/S2414314623002171 |
Sumario: | The crystal structure of the title enantiopure tetralol derivative {systematic name: (1S,2S)-2-[(S)-2,2,2-trifluoro-1-hydroxyethyl]-1,2,3,4-tetrahydronaphthalen-1-ol}, C(12)H(13)F(3)O(2), synthesized by asymmetric transfer hydrogenation, was elucidated by low-temperature single-crystal X-ray diffraction. The enantiopure compound crystallizes in the Sohncke space group P2(1)2(1)2(1) with one molecule in the asymmetric unit and features intramolecular as well as intermolecular O—H⋯O hydrogen bonding. The absolute configuration was established from anomalous dispersion effects. [Image: see text] |
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