Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid

Radioactive iodine (RAI) therapy is widely used and has an important role in the management of hyperthyroidism and thyroid malignancies. The development of acute or chronic leukemia is a very rare complication of RAI therapy. We report a case of metastatic Follicular thyroid cancer (FTC) who underwe...

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Autores principales: Bishnoi, Komal, Emerson, Ralph, Parida, Girish Kumar, Acharya, Prapti, Padhi, Somanath, Agrawal, Kanhaiyalal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171747/
https://www.ncbi.nlm.nih.gov/pubmed/37180180
http://dx.doi.org/10.4103/ijnm.ijnm_133_22
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author Bishnoi, Komal
Emerson, Ralph
Parida, Girish Kumar
Acharya, Prapti
Padhi, Somanath
Agrawal, Kanhaiyalal
author_facet Bishnoi, Komal
Emerson, Ralph
Parida, Girish Kumar
Acharya, Prapti
Padhi, Somanath
Agrawal, Kanhaiyalal
author_sort Bishnoi, Komal
collection PubMed
description Radioactive iodine (RAI) therapy is widely used and has an important role in the management of hyperthyroidism and thyroid malignancies. The development of acute or chronic leukemia is a very rare complication of RAI therapy. We report a case of metastatic Follicular thyroid cancer (FTC) who underwent total thyroidectomy followed by treatment with a cumulative dose of 1600 mCi of RAI (for 4 years) and by palliative radiotherapy for L4 spinal metastasis, later on, developed acute myeloid leukemia. Thus, all patients with thyroid carcinoma treated with RAI should undergo periodic hematological examinations irrespective of RAI dose.
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spelling pubmed-101717472023-05-11 Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid Bishnoi, Komal Emerson, Ralph Parida, Girish Kumar Acharya, Prapti Padhi, Somanath Agrawal, Kanhaiyalal Indian J Nucl Med Case Report Radioactive iodine (RAI) therapy is widely used and has an important role in the management of hyperthyroidism and thyroid malignancies. The development of acute or chronic leukemia is a very rare complication of RAI therapy. We report a case of metastatic Follicular thyroid cancer (FTC) who underwent total thyroidectomy followed by treatment with a cumulative dose of 1600 mCi of RAI (for 4 years) and by palliative radiotherapy for L4 spinal metastasis, later on, developed acute myeloid leukemia. Thus, all patients with thyroid carcinoma treated with RAI should undergo periodic hematological examinations irrespective of RAI dose. Wolters Kluwer - Medknow 2023 2023-02-24 /pmc/articles/PMC10171747/ /pubmed/37180180 http://dx.doi.org/10.4103/ijnm.ijnm_133_22 Text en Copyright: © 2023 Indian Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Bishnoi, Komal
Emerson, Ralph
Parida, Girish Kumar
Acharya, Prapti
Padhi, Somanath
Agrawal, Kanhaiyalal
Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid
title Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid
title_full Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid
title_fullStr Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid
title_full_unstemmed Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid
title_short Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid
title_sort acute myeloid leukemia following radioactive iodine therapy for metastatic follicular carcinoma of the thyroid
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171747/
https://www.ncbi.nlm.nih.gov/pubmed/37180180
http://dx.doi.org/10.4103/ijnm.ijnm_133_22
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