Intense Fluorodeoxyglucose Uptake in Aggressive Systemic Mastocytosis without Associated Hematological Neoplasm: Unusual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Presentation

Systemic mastocytosis (SM) is a relatively rare heterogeneous group of disorders characterized by uncontrolled proliferation and accumulation of clonal mast cells in one or more organs. Indolent SM is the most common variety. Less common variety is aggressive systemic mastocytosis (aSM) type with or...

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Autores principales: Fatima, Nosheen, Zaman, Areeba, Zaman, Sidra, Zaman, Unaiza, Zaman, Maseeh U. Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171754/
https://www.ncbi.nlm.nih.gov/pubmed/37180191
http://dx.doi.org/10.4103/ijnm.ijnm_88_22
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author Fatima, Nosheen
Zaman, Areeba
Zaman, Sidra
Zaman, Unaiza
Zaman, Maseeh U. Z.
author_facet Fatima, Nosheen
Zaman, Areeba
Zaman, Sidra
Zaman, Unaiza
Zaman, Maseeh U. Z.
author_sort Fatima, Nosheen
collection PubMed
description Systemic mastocytosis (SM) is a relatively rare heterogeneous group of disorders characterized by uncontrolled proliferation and accumulation of clonal mast cells in one or more organs. Indolent SM is the most common variety. Less common variety is aggressive systemic mastocytosis (aSM) type with or without associated hematological neopalsm (AHN). Fludeoxyglucose (FDG) positron emission tomography/computed tomography has a limited role in aSM without AHN as these exhibit low FDG avidity. We are presenting a biopsy-proven case of aSM without AHN showing abnormally high FDG uptake in lesions involving skin, nodes, marrow, and muscles.
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spelling pubmed-101717542023-05-11 Intense Fluorodeoxyglucose Uptake in Aggressive Systemic Mastocytosis without Associated Hematological Neoplasm: Unusual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Presentation Fatima, Nosheen Zaman, Areeba Zaman, Sidra Zaman, Unaiza Zaman, Maseeh U. Z. Indian J Nucl Med Interesting Image Systemic mastocytosis (SM) is a relatively rare heterogeneous group of disorders characterized by uncontrolled proliferation and accumulation of clonal mast cells in one or more organs. Indolent SM is the most common variety. Less common variety is aggressive systemic mastocytosis (aSM) type with or without associated hematological neopalsm (AHN). Fludeoxyglucose (FDG) positron emission tomography/computed tomography has a limited role in aSM without AHN as these exhibit low FDG avidity. We are presenting a biopsy-proven case of aSM without AHN showing abnormally high FDG uptake in lesions involving skin, nodes, marrow, and muscles. Wolters Kluwer - Medknow 2023 2023-02-24 /pmc/articles/PMC10171754/ /pubmed/37180191 http://dx.doi.org/10.4103/ijnm.ijnm_88_22 Text en Copyright: © 2023 Indian Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Fatima, Nosheen
Zaman, Areeba
Zaman, Sidra
Zaman, Unaiza
Zaman, Maseeh U. Z.
Intense Fluorodeoxyglucose Uptake in Aggressive Systemic Mastocytosis without Associated Hematological Neoplasm: Unusual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Presentation
title Intense Fluorodeoxyglucose Uptake in Aggressive Systemic Mastocytosis without Associated Hematological Neoplasm: Unusual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Presentation
title_full Intense Fluorodeoxyglucose Uptake in Aggressive Systemic Mastocytosis without Associated Hematological Neoplasm: Unusual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Presentation
title_fullStr Intense Fluorodeoxyglucose Uptake in Aggressive Systemic Mastocytosis without Associated Hematological Neoplasm: Unusual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Presentation
title_full_unstemmed Intense Fluorodeoxyglucose Uptake in Aggressive Systemic Mastocytosis without Associated Hematological Neoplasm: Unusual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Presentation
title_short Intense Fluorodeoxyglucose Uptake in Aggressive Systemic Mastocytosis without Associated Hematological Neoplasm: Unusual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Presentation
title_sort intense fluorodeoxyglucose uptake in aggressive systemic mastocytosis without associated hematological neoplasm: unusual fluorodeoxyglucose positron emission tomography/computed tomography presentation
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171754/
https://www.ncbi.nlm.nih.gov/pubmed/37180191
http://dx.doi.org/10.4103/ijnm.ijnm_88_22
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