The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review

Unlike apoptosis, pyroptosis, necroptosis, and ferroptosis are recently identified modes of programmed cell death (PCD) with unique molecular pathways. Increasing evidence has indicated that these PCD modes play a crucial role in the pathogenesis of various non-malignant dermatoses (a group of cutan...

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Autores principales: Teng, Yan, Xu, Danfeng, Yang, Xianhong, Tang, Hui, Tao, Xiaohua, Fan, Yibin, Ding, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171792/
https://www.ncbi.nlm.nih.gov/pubmed/37179755
http://dx.doi.org/10.2147/JIR.S409699
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author Teng, Yan
Xu, Danfeng
Yang, Xianhong
Tang, Hui
Tao, Xiaohua
Fan, Yibin
Ding, Yang
author_facet Teng, Yan
Xu, Danfeng
Yang, Xianhong
Tang, Hui
Tao, Xiaohua
Fan, Yibin
Ding, Yang
author_sort Teng, Yan
collection PubMed
description Unlike apoptosis, pyroptosis, necroptosis, and ferroptosis are recently identified modes of programmed cell death (PCD) with unique molecular pathways. Increasing evidence has indicated that these PCD modes play a crucial role in the pathogenesis of various non-malignant dermatoses (a group of cutaneous disorders), including infective dermatoses, immune-related dermatoses, allergic dermatoses, benign proliferative dermatoses, etc. Moreover, their molecular mechanisms have been suggested as potential therapeutic targets for the prevention and treatment of these dermatoses. In this article, we aim to review and summarize the molecular mechanisms of pyroptosis, necroptosis, and ferroptosis and their roles in the pathogenesis of some non-malignant dermatoses.
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spelling pubmed-101717922023-05-11 The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review Teng, Yan Xu, Danfeng Yang, Xianhong Tang, Hui Tao, Xiaohua Fan, Yibin Ding, Yang J Inflamm Res Review Unlike apoptosis, pyroptosis, necroptosis, and ferroptosis are recently identified modes of programmed cell death (PCD) with unique molecular pathways. Increasing evidence has indicated that these PCD modes play a crucial role in the pathogenesis of various non-malignant dermatoses (a group of cutaneous disorders), including infective dermatoses, immune-related dermatoses, allergic dermatoses, benign proliferative dermatoses, etc. Moreover, their molecular mechanisms have been suggested as potential therapeutic targets for the prevention and treatment of these dermatoses. In this article, we aim to review and summarize the molecular mechanisms of pyroptosis, necroptosis, and ferroptosis and their roles in the pathogenesis of some non-malignant dermatoses. Dove 2023-05-06 /pmc/articles/PMC10171792/ /pubmed/37179755 http://dx.doi.org/10.2147/JIR.S409699 Text en © 2023 Teng et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Teng, Yan
Xu, Danfeng
Yang, Xianhong
Tang, Hui
Tao, Xiaohua
Fan, Yibin
Ding, Yang
The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review
title The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review
title_full The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review
title_fullStr The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review
title_full_unstemmed The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review
title_short The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review
title_sort emerging roles of pyroptosis, necroptosis, and ferroptosis in non-malignant dermatoses: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171792/
https://www.ncbi.nlm.nih.gov/pubmed/37179755
http://dx.doi.org/10.2147/JIR.S409699
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