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A ratchet-like apical constriction drives cell ingression during the mouse gastrulation EMT

Epithelial-to-mesenchymal transition (EMT) is a fundamental process whereby epithelial cells acquire mesenchymal phenotypes and the ability to migrate. EMT is the hallmark of gastrulation, an evolutionarily conserved developmental process. In mammals, epiblast cells ingress at the primitive streak t...

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Detalles Bibliográficos
Autores principales: Francou, Alexandre, Anderson, Kathryn V, Hadjantonakis, Anna-Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171865/
https://www.ncbi.nlm.nih.gov/pubmed/37162187
http://dx.doi.org/10.7554/eLife.84019

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