Development of 2-chloroquinoline based heterocyclic frameworks as dual inhibitors of SARS-CoV-2 M(Pro) and PL(Pro)

Evolution of new variants of SARS-CoV-2 warrant the need for the continued efforts in identifying target-oriented new drugs. Dual targeting agents against M(Pro) and PL(Pro) not only overcome the incomplete efficacy but also the drug resistance, which is common problem. Since both these are cysteine...

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Detalles Bibliográficos
Autores principales: Kattula, Bhavita, Reddi, Bharati, Jangam, Aruna, Naik, Lekhika, Adimoolam, Bala Manikanta, Vavilapalli, Suresh, Are, Sayanna, Thota, Jagadeshwar Reddy, Jadav, Surender Singh, Arifuddin, Mohammed, Addlagatta, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171901/
https://www.ncbi.nlm.nih.gov/pubmed/37172706
http://dx.doi.org/10.1016/j.ijbiomac.2023.124772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171901/
https://www.ncbi.nlm.nih.gov/pubmed/37172706
http://dx.doi.org/10.1016/j.ijbiomac.2023.124772

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