Cargando…
Development of 2-chloroquinoline based heterocyclic frameworks as dual inhibitors of SARS-CoV-2 M(Pro) and PL(Pro)
Evolution of new variants of SARS-CoV-2 warrant the need for the continued efforts in identifying target-oriented new drugs. Dual targeting agents against M(Pro) and PL(Pro) not only overcome the incomplete efficacy but also the drug resistance, which is common problem. Since both these are cysteine...
Autores principales: | Kattula, Bhavita, Reddi, Bharati, Jangam, Aruna, Naik, Lekhika, Adimoolam, Bala Manikanta, Vavilapalli, Suresh, Are, Sayanna, Thota, Jagadeshwar Reddy, Jadav, Surender Singh, Arifuddin, Mohammed, Addlagatta, Anthony |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171901/ https://www.ncbi.nlm.nih.gov/pubmed/37172706 http://dx.doi.org/10.1016/j.ijbiomac.2023.124772 |
Ejemplares similares
-
Anti-inflammatory and antioxidant activities of Gymnema Sylvestre extract rescue acute respiratory distress syndrome in rats via modulating the NF-κB/MAPK pathway
por: Jangam, Aruna, et al.
Publicado: (2023) -
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach
por: Goudshelwar, Renuka, et al.
Publicado: (2022) -
Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PL(PRO) and 3CL(PRO) proteases
por: Jade, Dhananjay, et al.
Publicado: (2021) -
Discovery of PL(pro) and M(pro) Inhibitors
for SARS-CoV-2
por: Puhl, Ana C., et al.
Publicado: (2023) -
Synthetic and Medicinal
Chemistry Approaches Toward
WEE1 Kinase Inhibitors and Its Degraders
por: Alli, Vidya Jyothi, et al.
Publicado: (2023)