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A Case Report of Brucellosis-Associated Infective Endocarditis

Brucellosis is a prevalent zoonotic infection that can be relatively well managed and tolerated if appropriate treatment is initiated. Unfortunately, likely secondary to decreased awareness and vague symptoms, the diagnosis can be easily missed leading to worsening complications that severely increa...

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Autores principales: Zaidi, Syed Muhammad Hussain, Iskander, Peter A, Choudhry, Muhammad Saad, Iskander, Anthony, Ahmed, Khalid, Nasar, Simin, Klamp, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171988/
https://www.ncbi.nlm.nih.gov/pubmed/37182001
http://dx.doi.org/10.7759/cureus.37407
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author Zaidi, Syed Muhammad Hussain
Iskander, Peter A
Choudhry, Muhammad Saad
Iskander, Anthony
Ahmed, Khalid
Nasar, Simin
Klamp, Douglas
author_facet Zaidi, Syed Muhammad Hussain
Iskander, Peter A
Choudhry, Muhammad Saad
Iskander, Anthony
Ahmed, Khalid
Nasar, Simin
Klamp, Douglas
author_sort Zaidi, Syed Muhammad Hussain
collection PubMed
description Brucellosis is a prevalent zoonotic infection that can be relatively well managed and tolerated if appropriate treatment is initiated. Unfortunately, likely secondary to decreased awareness and vague symptoms, the diagnosis can be easily missed leading to worsening complications that severely increase the mortality rate. We present a case of a 25-year-old female who presented from a rural setting with a diagnosis of brucellosis, which was delayed. She ultimately developed infective endocarditis with cardiac vegetations on imaging. Despite improvement on antibiotics and reduction in size of cardiac vegetation, she suffered a fatal cardiac arrest before undergoing surgical intervention. Better awareness regarding hygiene and sanitary food handling should be encouraged, especially in underdeveloped rural areas, to help prevent infection. More studies need to be performed to help better identify symptoms coupled with maintaining a high index of suspicion so as to expedite diagnosis, treatment, management and hopefully prevent the progression of disease and worsening complications.
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spelling pubmed-101719882023-05-11 A Case Report of Brucellosis-Associated Infective Endocarditis Zaidi, Syed Muhammad Hussain Iskander, Peter A Choudhry, Muhammad Saad Iskander, Anthony Ahmed, Khalid Nasar, Simin Klamp, Douglas Cureus Cardiology Brucellosis is a prevalent zoonotic infection that can be relatively well managed and tolerated if appropriate treatment is initiated. Unfortunately, likely secondary to decreased awareness and vague symptoms, the diagnosis can be easily missed leading to worsening complications that severely increase the mortality rate. We present a case of a 25-year-old female who presented from a rural setting with a diagnosis of brucellosis, which was delayed. She ultimately developed infective endocarditis with cardiac vegetations on imaging. Despite improvement on antibiotics and reduction in size of cardiac vegetation, she suffered a fatal cardiac arrest before undergoing surgical intervention. Better awareness regarding hygiene and sanitary food handling should be encouraged, especially in underdeveloped rural areas, to help prevent infection. More studies need to be performed to help better identify symptoms coupled with maintaining a high index of suspicion so as to expedite diagnosis, treatment, management and hopefully prevent the progression of disease and worsening complications. Cureus 2023-04-10 /pmc/articles/PMC10171988/ /pubmed/37182001 http://dx.doi.org/10.7759/cureus.37407 Text en Copyright © 2023, Zaidi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Zaidi, Syed Muhammad Hussain
Iskander, Peter A
Choudhry, Muhammad Saad
Iskander, Anthony
Ahmed, Khalid
Nasar, Simin
Klamp, Douglas
A Case Report of Brucellosis-Associated Infective Endocarditis
title A Case Report of Brucellosis-Associated Infective Endocarditis
title_full A Case Report of Brucellosis-Associated Infective Endocarditis
title_fullStr A Case Report of Brucellosis-Associated Infective Endocarditis
title_full_unstemmed A Case Report of Brucellosis-Associated Infective Endocarditis
title_short A Case Report of Brucellosis-Associated Infective Endocarditis
title_sort case report of brucellosis-associated infective endocarditis
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171988/
https://www.ncbi.nlm.nih.gov/pubmed/37182001
http://dx.doi.org/10.7759/cureus.37407
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