Pro-inflammatory RNA:DNA Hybrids Are p53 Independently Boosted by Hyperbaric Oxygen: a Subcellular Distribution Analysis by Automated Quantitative Imaging

PURPOSE: RNA:DNA hybrids are co-transcriptional products with acknowledged cytoplasmic pro-inflammatory role as activators of the cGAS-STING pathway. We recently proved them also as radiation-induced senescence messages for the abscopal effect mediation, demonstrating the need for a functional p53 f...

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Detalles Bibliográficos
Autores principales: De Santis, Ilaria, Zanoni, Michele, Pignatta, Sara, Longobardi, Pasquale, Tesei, Anna, Bevilacqua, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172224/
https://www.ncbi.nlm.nih.gov/pubmed/36261778
http://dx.doi.org/10.1007/s11307-022-01778-2

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