Cargando…

Radiosynthesis and Analysis of (S)-4-(3-[(18)F]Fluoropropyl)-L-Glutamic Acid

PURPOSE: (S)-4-(3-[(18)F]Fluoropropyl)-L-glutamic acid ([(18)F]FSPG) is an L-glutamate derivative used as a PET biomarker to assess intracellular redox status in vivo through targeting of the cystine/glutamate antiporter protein, x(c)(−) transporter. In this report, we describe a radiosynthesis of [...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brown, Gavin, Soloviev, Dmitry, Lewis, David Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172245/ https://www.ncbi.nlm.nih.gov/pubmed/36525163 http://dx.doi.org/10.1007/s11307-022-01793-3

Ejemplares similares

Synthesis and analysis of 4-(3-fluoropropyl)-glutamic acid stereoisomers to determine the stereochemical purity of (4S)-4-(3-[(18)F]fluoropropyl)-L-glutamic acid ([(18)F]FSPG) for clinical use
por: Shih, Kai-Ting, et al.
Publicado: (2020)

Pilot Preclinical and Clinical Evaluation of (4S)-4-(3-[18F]Fluoropropyl)-L-Glutamate (18F-FSPG) for PET/CT Imaging of Intracranial Malignancies
por: Mittra, Erik S., et al.
Publicado: (2016)

[(18)F](2S,4S)-4-(3-Fluoropropyl)glutamine as a Tumor Imaging Agent
por: Wu, Zehui, et al.
Publicado: (2014)

Initial evaluation of (4S)-4-(3-[(18)F]fluoropropyl)-l-glutamate (FSPG) PET/CT imaging in patients with head and neck cancer, colorectal cancer, or non-Hodgkin lymphoma
por: Park, Sonya Y., et al.
Publicado: (2020)

Radiosynthesis and Biological Evaluation of N-[(18)F]Labeled Glutamic Acid as a Tumor Metabolic Imaging Tracer
por: Hu, Kongzhen, et al.
Publicado: (2014)

Synthesis and Biological Evaluation of O-[3-(18)F-fluoropropyl]-α-methyl Tyrosine in Mesothelioma-Bearing Rodents
por: Shih, I-Hong, et al.
Publicado: (2013)

Automated Radiosynthesis of cis- and trans-4-[(18)F]Fluoro-l-proline Using [(18)F]Fluoride
por: Morgan, Timaeus E. F., et al.
Publicado: (2021)

Radiosynthesis of [(18)F]Trifluoroalkyl Groups: Scope and Limitations
por: Lien, V. T., et al.
Publicado: (2014)

Radiosynthesis and Evaluation of an (18)F-Labeled Positron Emission Tomography (PET) Radioligand for Metabotropic Glutamate Receptor Subtype 4 (mGlu(4))
por: Kil, Kun-Eek, et al.
Publicado: (2014)

Radiosynthesis of [(18)F]-Labelled Pro-Nucleotides (ProTides)
por: Cavaliere, Alessandra, et al.
Publicado: (2020)

Fully Automated, High-Dose Radiosynthesis of [(18)F]PARPi
por: Pacelli, Anna, et al.
Publicado: (2022)

An updated radiosynthesis of [(18)F]AV1451 for tau PET imaging
por: Mossine, Andrew V., et al.
Publicado: (2017)

Robust and Facile Automated Radiosynthesis of [(18)F]FSPG on the GE FASTlab
por: Edwards, Richard, et al.
Publicado: (2021)

A simple and efficient automated microvolume radiosynthesis of [(18)F]Florbetaben
por: Lisova, Ksenia, et al.
Publicado: (2020)

On-demand radiosynthesis of N-succinimidyl-4-[(18)F]fluorobenzoate ([(18)F]SFB) on an electrowetting-on-dielectric microfluidic chip for (18)F-labeling of protein
por: Kim, Hee-Kwon, et al.
Publicado: (2019)

Radiosynthesis and pharmacokinetics of [(18)F]fluoroethyl bufalin in hepatocellular carcinoma-bearing mice
por: Yang, Zhaoshuo, et al.
Publicado: (2017)

Automation of the Radiosynthesis of Six Different (18)F-labeled radiotracers on the AllinOne
por: Li, Shihong, et al.
Publicado: (2016)

Radiosynthesis of the norepinephrine transporter tracer [(18)F]NS12137 via copper‐mediated (18) F‐labelling
por: Lahdenpohja, Salla, et al.
Publicado: (2019)

High molar activity [(18)F]tetrafluoroborate synthesis for sodium iodide symporter imaging by PET
por: Soloviev, Dmitry, et al.
Publicado: (2022)

Radiosynthesis of the anticancer nucleoside analogue Trifluridine using an automated (18)F-trifluoromethylation procedure
por: King, Alice, et al.
Publicado: (2018)

Radiosynthesis of 5-[(18)F]Fluoro-1,2,3-triazoles through Aqueous Iodine–[(18)F]Fluorine Exchange Reaction
por: Zhang, Xiang, et al.
Publicado: (2021)

PET Imaging a MPTP-Induced Mouse Model of Parkinson’s Disease Using the Fluoropropyl-Dihydrotetrabenazine Analog [(18)F]-DTBZ (AV-133)
por: Toomey, James S., et al.
Publicado: (2012)

A Multi-Atlas-Based [18F]9-Fluoropropyl-(+)-Dihydrotetrabenazine Positron Emission Tomography Image Segmentation Method for Parkinson’s Disease Quantification
por: Pan, Yiwei, et al.
Publicado: (2022)

(18)F-Labelled Intermediates for Radiosynthesis by Modular Build-Up Reactions: Newer Developments
por: Ermert, Johannes
Publicado: (2014)

Automated radiosynthesis of two (18)F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [(18)F]FMISO and [(18)F]PM-PBB3, via [(18)F]epifluorohydrin
por: Ohkubo, Takayuki, et al.
Publicado: (2021)

An improved radiosynthesis of [(18)F]FAraG, a PET radiotracer for imaging T‐cell activation
por: Holt, Daniel P., et al.
Publicado: (2022)

One-Step Automatic Radiosynthesis and Evaluation of [(18)F]TM-30089 as GPR44 Radiotracer
por: Peng, Jiangling, et al.
Publicado: (2023)

Radiosynthesis and reactivity of N-[(11)C]methyl carbamoylimidazole
por: Kadirvel, Manikandan, et al.
Publicado: (2018)

Quantitative analysis of the therapeutic effect of magnolol on MPTP-induced mouse model of Parkinson’s disease using in vivo (18)F-9-fluoropropyl-(+)-dihydrotetrabenazine PET imaging
por: Weng, Chi-Chang, et al.
Publicado: (2017)

Radiosynthesis and evaluation of an (18)F–labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma
por: Dialer, Lukas O., et al.
Publicado: (2018)

Radiosynthesis and preliminary biological evaluation of N-(2-[(18)F]fluoropropionyl)-L-glutamine as a PET tracer for tumor imaging
por: Tang, Caihua, et al.
Publicado: (2016)

One-step radiosynthesis of the MCTs imaging agent [(18)F]FACH by aliphatic (18)F-labelling of a methylsulfonate precursor containing an unprotected carboxylic acid group
por: Sadeghzadeh, Masoud, et al.
Publicado: (2019)

Microfluidic radiosynthesis of [(18)F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors
por: Collier, Thomas Lee, et al.
Publicado: (2017)

Revisiting the Radiosynthesis of [(18)F]FPEB and Preliminary PET Imaging in a Mouse Model of Alzheimer’s Disease
por: Varlow, Cassis, et al.
Publicado: (2020)

GMP-Compliant Radiosynthesis of [(18)F]GP1, a Novel PET Tracer for the Detection of Thrombi
por: Hugenberg, Verena, et al.
Publicado: (2021)

Evaluating Hepatobiliary Transport with (18)F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and In Vitro and In Vivo Performance
por: De Lombaerde, Stef, et al.
Publicado: (2018)

Reliable radiosynthesis of 4-[(10)B]borono-2-[(18)F]fluoro-l-phenylalanine with quality assurance for boron neutron capture therapy-oriented diagnosis
por: Ishiwata, Kiichi, et al.
Publicado: (2018)

Radiosynthesis and Preliminary Biological Evaluation of (18)F-Fluoropropionyl-Chlorotoxin as a Potential PET Tracer for Glioma Imaging
por: Zhao, Jing, et al.
Publicado: (2018)

Optimized and Automated Radiosynthesis of [(18)F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography
por: Zhang, Wenjie, et al.
Publicado: (2016)

Clinical Radiosynthesis and Translation of [(18)F]OP-801: A Novel Radiotracer for Imaging Reactive Microglia and Macrophages
por: Jackson, Isaac M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qo51l1nfhtf6qm37u9p205usqk