Measurement of Protein Synthesis Rate in Rat by [(11)C]Leucine PET Imaging: Application to the TgF344-AD Model of Alzheimer’s Disease

Long-term memory requires stable protein synthesis and is altered in Alzheimer’s disease (AD). This study aimed to implement a method to measure the cerebral protein synthesis rate (PSR) with [(11)C]leucine PET in vivo in rats and evaluate potential PSR alterations longitudinally (6, 12 and 18 month...

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Detalles Bibliográficos
Autores principales: Bochicchio, D., Christie, L., Lawrence, C. B., Herholz, K., Parker, C. A., Hinz, R., Boutin, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172255/
https://www.ncbi.nlm.nih.gov/pubmed/36538180
http://dx.doi.org/10.1007/s11307-022-01796-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172255/
https://www.ncbi.nlm.nih.gov/pubmed/36538180
http://dx.doi.org/10.1007/s11307-022-01796-0

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