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Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge
PURPOSE: To support acquisition of accurate, reproducible and high-quality preclinical imaging data, various standardisation resources have been developed over the years. However, it is unclear the impact of those efforts in current preclinical imaging practices. To better understand the status quo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172263/ https://www.ncbi.nlm.nih.gov/pubmed/36482032 http://dx.doi.org/10.1007/s11307-022-01790-6 |
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author | Tavares, Adriana A. S. Mezzanotte, Laura McDougald, Wendy Bernsen, Monique R. Vanhove, Christian Aswendt, Markus Ielacqua, Giovanna D. Gremse, Felix Moran, Carmel M. Warnock, Geoff Kuntner, Claudia Huisman, Marc C. |
author_facet | Tavares, Adriana A. S. Mezzanotte, Laura McDougald, Wendy Bernsen, Monique R. Vanhove, Christian Aswendt, Markus Ielacqua, Giovanna D. Gremse, Felix Moran, Carmel M. Warnock, Geoff Kuntner, Claudia Huisman, Marc C. |
author_sort | Tavares, Adriana A. S. |
collection | PubMed |
description | PURPOSE: To support acquisition of accurate, reproducible and high-quality preclinical imaging data, various standardisation resources have been developed over the years. However, it is unclear the impact of those efforts in current preclinical imaging practices. To better understand the status quo in the field of preclinical imaging standardisation, the STANDARD group of the European Society of Molecular Imaging (ESMI) put together a community survey and a forum for discussion at the European Molecular Imaging Meeting (EMIM) 2022. This paper reports on the results from the STANDARD survey and the forum discussions that took place at EMIM2022. PROCEDURES: The survey was delivered to the community by the ESMI office and was promoted through the Society channels, email lists and webpages. The survey contained seven sections organised as generic questions and imaging modality-specific questions. The generic questions focused on issues regarding data acquisition, data processing, data storage, publishing and community awareness of international guidelines for animal research. Specific questions on practices in optical imaging, PET, CT, SPECT, MRI and ultrasound were further included. RESULTS: Data from the STANDARD survey showed that 47% of survey participants do not have or do not know if they have QC/QA guidelines at their institutes. Additionally, a large variability exists in the ways data are acquired, processed and reported regarding general aspects as well as modality-specific aspects. Moreover, there is limited awareness of the existence of international guidelines on preclinical (imaging) research practices. CONCLUSIONS: Standardisation of preclinical imaging techniques remains a challenge and hinders the transformative potential of preclinical imaging to augment biomedical research pipelines by serving as an easy vehicle for translation of research findings to the clinic. Data collected in this project show that there is a need to promote and disseminate already available tools to standardise preclinical imaging practices. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11307-022-01790-6. |
format | Online Article Text |
id | pubmed-10172263 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-101722632023-05-12 Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge Tavares, Adriana A. S. Mezzanotte, Laura McDougald, Wendy Bernsen, Monique R. Vanhove, Christian Aswendt, Markus Ielacqua, Giovanna D. Gremse, Felix Moran, Carmel M. Warnock, Geoff Kuntner, Claudia Huisman, Marc C. Mol Imaging Biol Research Article PURPOSE: To support acquisition of accurate, reproducible and high-quality preclinical imaging data, various standardisation resources have been developed over the years. However, it is unclear the impact of those efforts in current preclinical imaging practices. To better understand the status quo in the field of preclinical imaging standardisation, the STANDARD group of the European Society of Molecular Imaging (ESMI) put together a community survey and a forum for discussion at the European Molecular Imaging Meeting (EMIM) 2022. This paper reports on the results from the STANDARD survey and the forum discussions that took place at EMIM2022. PROCEDURES: The survey was delivered to the community by the ESMI office and was promoted through the Society channels, email lists and webpages. The survey contained seven sections organised as generic questions and imaging modality-specific questions. The generic questions focused on issues regarding data acquisition, data processing, data storage, publishing and community awareness of international guidelines for animal research. Specific questions on practices in optical imaging, PET, CT, SPECT, MRI and ultrasound were further included. RESULTS: Data from the STANDARD survey showed that 47% of survey participants do not have or do not know if they have QC/QA guidelines at their institutes. Additionally, a large variability exists in the ways data are acquired, processed and reported regarding general aspects as well as modality-specific aspects. Moreover, there is limited awareness of the existence of international guidelines on preclinical (imaging) research practices. CONCLUSIONS: Standardisation of preclinical imaging techniques remains a challenge and hinders the transformative potential of preclinical imaging to augment biomedical research pipelines by serving as an easy vehicle for translation of research findings to the clinic. Data collected in this project show that there is a need to promote and disseminate already available tools to standardise preclinical imaging practices. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11307-022-01790-6. Springer International Publishing 2022-12-08 2023 /pmc/articles/PMC10172263/ /pubmed/36482032 http://dx.doi.org/10.1007/s11307-022-01790-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Research Article Tavares, Adriana A. S. Mezzanotte, Laura McDougald, Wendy Bernsen, Monique R. Vanhove, Christian Aswendt, Markus Ielacqua, Giovanna D. Gremse, Felix Moran, Carmel M. Warnock, Geoff Kuntner, Claudia Huisman, Marc C. Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge |
title | Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge |
title_full | Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge |
title_fullStr | Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge |
title_full_unstemmed | Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge |
title_short | Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge |
title_sort | community survey results show that standardisation of preclinical imaging techniques remains a challenge |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172263/ https://www.ncbi.nlm.nih.gov/pubmed/36482032 http://dx.doi.org/10.1007/s11307-022-01790-6 |
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