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Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss

This study is the first to demonstrate that deep ocean water (DOW) has physiological significant effects on squid. After 36 h of rearing squids, those reared with DOW had significantly higher total and free cholesterol levels and lower alanine transaminase activity in hemolymph as compared with thos...

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Autores principales: Hatano, Kaito, Yoshida, Masa-Aki, Hirayama, Jun, Kitani, Yoichiro, Hattori, Atsuhiko, Ogiso, Shouzo, Watabe, Yukina, Sekiguchi, Toshio, Tabuchi, Yoshiaki, Urata, Makoto, Matsumoto, Kyoko, Sakatoku, Akihiro, Srivastav, Ajai K., Toyota, Kenji, Matsubara, Hajime, Suzuki, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172372/
https://www.ncbi.nlm.nih.gov/pubmed/37164992
http://dx.doi.org/10.1038/s41598-023-34443-x
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author Hatano, Kaito
Yoshida, Masa-Aki
Hirayama, Jun
Kitani, Yoichiro
Hattori, Atsuhiko
Ogiso, Shouzo
Watabe, Yukina
Sekiguchi, Toshio
Tabuchi, Yoshiaki
Urata, Makoto
Matsumoto, Kyoko
Sakatoku, Akihiro
Srivastav, Ajai K.
Toyota, Kenji
Matsubara, Hajime
Suzuki, Nobuo
author_facet Hatano, Kaito
Yoshida, Masa-Aki
Hirayama, Jun
Kitani, Yoichiro
Hattori, Atsuhiko
Ogiso, Shouzo
Watabe, Yukina
Sekiguchi, Toshio
Tabuchi, Yoshiaki
Urata, Makoto
Matsumoto, Kyoko
Sakatoku, Akihiro
Srivastav, Ajai K.
Toyota, Kenji
Matsubara, Hajime
Suzuki, Nobuo
author_sort Hatano, Kaito
collection PubMed
description This study is the first to demonstrate that deep ocean water (DOW) has physiological significant effects on squid. After 36 h of rearing squids, those reared with DOW had significantly higher total and free cholesterol levels and lower alanine transaminase activity in hemolymph as compared with those reared with surface sea water (SSW). SSW rearing also resulted in 6.95% weight loss, while DOW rearing caused only 2.5% weight loss, which might be due to liver metabolism suppression. Furthermore, both monovalent (sodium, chloride, and potassium ions) and divalent (calcium, inorganic phosphorus, and magnesium ions) ions in hemolymph were elevated when reared with DOW compared to those when reared with SSW. A study of genes expressed in the brain revealed that five genes were specifically remarked in DOW rearing. Most altered genes were neuropeptides, including those from vasopressin superfamily. These neuropeptides are involved in cholesterol and/or mineral metabolisms and physiological significant effects on squid. This study is the first report the effects of DOW on cholesterol and mineral metabolism of squid and will contribute to squid aquaculture using DOW.
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spelling pubmed-101723722023-05-12 Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss Hatano, Kaito Yoshida, Masa-Aki Hirayama, Jun Kitani, Yoichiro Hattori, Atsuhiko Ogiso, Shouzo Watabe, Yukina Sekiguchi, Toshio Tabuchi, Yoshiaki Urata, Makoto Matsumoto, Kyoko Sakatoku, Akihiro Srivastav, Ajai K. Toyota, Kenji Matsubara, Hajime Suzuki, Nobuo Sci Rep Article This study is the first to demonstrate that deep ocean water (DOW) has physiological significant effects on squid. After 36 h of rearing squids, those reared with DOW had significantly higher total and free cholesterol levels and lower alanine transaminase activity in hemolymph as compared with those reared with surface sea water (SSW). SSW rearing also resulted in 6.95% weight loss, while DOW rearing caused only 2.5% weight loss, which might be due to liver metabolism suppression. Furthermore, both monovalent (sodium, chloride, and potassium ions) and divalent (calcium, inorganic phosphorus, and magnesium ions) ions in hemolymph were elevated when reared with DOW compared to those when reared with SSW. A study of genes expressed in the brain revealed that five genes were specifically remarked in DOW rearing. Most altered genes were neuropeptides, including those from vasopressin superfamily. These neuropeptides are involved in cholesterol and/or mineral metabolisms and physiological significant effects on squid. This study is the first report the effects of DOW on cholesterol and mineral metabolism of squid and will contribute to squid aquaculture using DOW. Nature Publishing Group UK 2023-05-10 /pmc/articles/PMC10172372/ /pubmed/37164992 http://dx.doi.org/10.1038/s41598-023-34443-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hatano, Kaito
Yoshida, Masa-Aki
Hirayama, Jun
Kitani, Yoichiro
Hattori, Atsuhiko
Ogiso, Shouzo
Watabe, Yukina
Sekiguchi, Toshio
Tabuchi, Yoshiaki
Urata, Makoto
Matsumoto, Kyoko
Sakatoku, Akihiro
Srivastav, Ajai K.
Toyota, Kenji
Matsubara, Hajime
Suzuki, Nobuo
Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss
title Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss
title_full Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss
title_fullStr Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss
title_full_unstemmed Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss
title_short Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss
title_sort deep ocean water alters the cholesterol and mineral metabolism of squid todarodes pacificus and suppresses its weight loss
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172372/
https://www.ncbi.nlm.nih.gov/pubmed/37164992
http://dx.doi.org/10.1038/s41598-023-34443-x
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