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Discovery of a highly efficient TylF methyltransferase via random mutagenesis for improving tylosin production

Macrolides are currently a class of extensively used antibiotics in human and animal medicine. Tylosin is not only one of the most important veterinary macrolides but also an indispensable material for the bio- and chemo-synthesis of new generations of macrolide antibiotics. Thus, improving its prod...

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Detalles Bibliográficos
Autores principales:	Fan, Jingyan, Yao, Zhiming, Yan, Chaoyue, Hao, Meilin, Dai, Jun, Zou, Wenjin, Ni, Minghui, Li, Tingting, Li, Lu, Li, Shuo, Liu, Jie, Huang, Qi, Zhou, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172623/ https://www.ncbi.nlm.nih.gov/pubmed/37181661 http://dx.doi.org/10.1016/j.csbj.2023.04.005

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