SENP3 deletion promotes M2 macrophage polarization and accelerates wound healing through smad6/IκB/p65 signaling pathway

Macrophages preferentially polarize to the anti-inflammatory M2 subtype in response to alterations in the wound microenvironment. SUMO-specific protease 3 (SENP3), a SUMO-specific protease, has been proven to regulate inflammation in macrophages by deSUMOylating substrate proteins, but its contribut...

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Detalles Bibliográficos
Autores principales: Ma, Yiwen, Hu, Jiateng, Xue, Xingjuan, Gu, Jianmin, Pan, Yuyan, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172869/
https://www.ncbi.nlm.nih.gov/pubmed/37180935
http://dx.doi.org/10.1016/j.heliyon.2023.e15584

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