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Maturation of the malarial phosphatidylserine decarboxylase is mediated by high affinity binding to anionic phospholipids

Decarboxylation of phosphatidylserine (PS) to form phosphatidylethanolamine by PS decarboxylases (PSDs) is an essential process in most eukaryotes. Processing of a malarial PSD proenzyme into its active alpha and beta subunits is by an autoendoproteolytic mechanism regulated by anionic phospholipids...

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Detalles Bibliográficos
Autores principales: Choi, Jae-Yeon, Lopes, Lauren, Ben Mamoun, Choukri, Voelker, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172927/
https://www.ncbi.nlm.nih.gov/pubmed/36997087
http://dx.doi.org/10.1016/j.jbc.2023.104659