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An Automated, Home-Cage, Video Monitoring-based Mouse Frailty Index Detects Age-associated Morbidity in C57BL/6 and Diversity Outbred Mice

Frailty indexes (FIs) provide quantitative measurements of nonspecific health decline and are particularly useful as longitudinal monitors of morbidity in aging studies. For mouse studies, frailty assessments can be taken noninvasively, but they require handling and direct observation that is labor-...

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Detalles Bibliográficos
Autores principales: Ruby, J Graham, Di Francesco, Andrea, Ylagan, Paulo, Luo, Angela, Keyser, Robert, Williams, Owen, Spock, Sarah, Li, Wenzhou, Vongtharangsy, Nalien, Chatterjee, Sandip, Sloan, Cricket A, Ledogar, Charles, Kuiper, Veronica, Kite, Janessa, Cosino, Marcelo, Cha, Paulyn, Karlsson, Eleanor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172975/
https://www.ncbi.nlm.nih.gov/pubmed/36708182
http://dx.doi.org/10.1093/gerona/glad035