Dyskeratosis Congenita Links Telomere Attrition to 
Age-Related Systemic Energetics

The underlying mechanisms of plasma metabolite signatures of human aging and age-related diseases are not clear but telomere attrition and dysfunction are central to both. Dyskeratosis congenita (DC) is associated with mutations in the telomerase enzyme complex (TERT, TERC, and DKC1) and progressive...

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Detalles Bibliográficos
Autores principales: James, Emma Naomi, Sagi-Kiss, Virag, Bennett, Mark, Mycielska, Maria Elzbieta, Karen-Ng, Lee Peng, Roberts, Terry, Matta, Sheila, Dokal, Inderjeet, Bundy, Jacob Guy, Parkinson, Eric Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172980/
https://www.ncbi.nlm.nih.gov/pubmed/36651908
http://dx.doi.org/10.1093/gerona/glad018

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