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Total synthesis of (−)-scabrolide A and (−)-yonarolide

The complete account of the total syntheses of scabrolide A and yonarolide is disclosed. This article describes an initial approach involving a bio-inspired macrocyclization/transannular Diels–Alder cascade, which ultimately failed due to undesired reactivity during macrocycle construction. Next, th...

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Detalles Bibliográficos
Autores principales:	Hafeman, Nicholas J., Loskot, Steven A., Reimann, Christopher E., Pritchett, Beau P., Virgil, Scott C., Stoltz, Brian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173254/ https://www.ncbi.nlm.nih.gov/pubmed/37181769 http://dx.doi.org/10.1039/d3sc00651d

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