Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations

This case–control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated va...

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Autores principales: Mills, Alexandra G., Dupper, Amy C., Chacko, Kieran I., Alburquerque, Bremy, Nadkarni, Devika, Berbel Caban, Ana, Fox, Lindsey, Gitman, Melissa R., Obla, Ajay, van Bakel, Harm, Altman, Deena R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Concise Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173282/
https://www.ncbi.nlm.nih.gov/pubmed/37179762
http://dx.doi.org/10.1017/ash.2023.163
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author Mills, Alexandra G.
Dupper, Amy C.
Chacko, Kieran I.
Alburquerque, Bremy
Nadkarni, Devika
Berbel Caban, Ana
Fox, Lindsey
Gitman, Melissa R.
Obla, Ajay
van Bakel, Harm
Altman, Deena R.
author_facet Mills, Alexandra G.
Dupper, Amy C.
Chacko, Kieran I.
Alburquerque, Bremy
Nadkarni, Devika
Berbel Caban, Ana
Fox, Lindsey
Gitman, Melissa R.
Obla, Ajay
van Bakel, Harm
Altman, Deena R.
author_sort Mills, Alexandra G.
collection PubMed
description This case–control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated vancomycin MIC. Elevated vancomycin MIC was associated with baseline hemodialysis, prior MRSA colonization, and metastatic infection.
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spelling pubmed-101732822023-05-12 Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations Mills, Alexandra G. Dupper, Amy C. Chacko, Kieran I. Alburquerque, Bremy Nadkarni, Devika Berbel Caban, Ana Fox, Lindsey Gitman, Melissa R. Obla, Ajay van Bakel, Harm Altman, Deena R. Antimicrob Steward Healthc Epidemiol Concise Communication This case–control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated vancomycin MIC. Elevated vancomycin MIC was associated with baseline hemodialysis, prior MRSA colonization, and metastatic infection. Cambridge University Press 2023-05-02 /pmc/articles/PMC10173282/ /pubmed/37179762 http://dx.doi.org/10.1017/ash.2023.163 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
spellingShingle Concise Communication
Mills, Alexandra G.
Dupper, Amy C.
Chacko, Kieran I.
Alburquerque, Bremy
Nadkarni, Devika
Berbel Caban, Ana
Fox, Lindsey
Gitman, Melissa R.
Obla, Ajay
van Bakel, Harm
Altman, Deena R.
Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations
title Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations
title_full Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations
title_fullStr Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations
title_full_unstemmed Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations
title_short Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations
title_sort methicillin-resistant staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations
topic Concise Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173282/
https://www.ncbi.nlm.nih.gov/pubmed/37179762
http://dx.doi.org/10.1017/ash.2023.163
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