Isoflavonoid and Furanochromone Natural Products as Potential DNA Gyrase Inhibitors: Computational, Spectral, and Antimycobacterial Studies

[Image: see text] In pursuit of new antitubercular agents, we here report the antimycobacterial (H(37)Rv) and DNA gyrase inhibitory potential of daidzein and khellin natural products (NPs). We procured a total of 16 NPs based on their pharmacophoric similarities with known antimycobacterial compound...

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Detalles Bibliográficos
Autores principales: Jagatap, Vilas R., Ahmad, Iqrar, Sriram, Dharmarajan, Kumari, Jyothi, Adu, Darko Kwabena, Ike, Blessing Wisdom, Ghai, Meenu, Ansari, Siddique Akber, Ansari, Irfan Aamer, Wetchoua, Priscille Ornella Mefotso, Karpoormath, Rajshekhar, Patel, Harun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173323/
https://www.ncbi.nlm.nih.gov/pubmed/37179626
http://dx.doi.org/10.1021/acsomega.3c00684

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