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C3 Functionalization of Indolizines via HFIP-Promoted Friedel–Crafts Reactions with (Hetero)arylglyoxals

[Image: see text] A highly efficient Friedel–Crafts type hydroxyalkylation at the C3 position of indolizines with (hetero)arylglyoxals has been achieved by the action of hexafluoroisopropanol (HFIP) under mild reaction conditions, leading to direct access to a variety of polyfunctionalized indolizin...

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Detalles Bibliográficos
Autores principales:	Jung, Euijin, Jeong, Yerin, Kim, Hyeyeon, Kim, Ikyon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173336/ https://www.ncbi.nlm.nih.gov/pubmed/37179639 http://dx.doi.org/10.1021/acsomega.3c00236

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