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Influence of the sickle cell trait on Plasmodium falciparum infectivity from naturally infected gametocyte carriers

BACKGROUND: Sickle cell trait (SCT) refers to the carriage of one abnormal copy of the β-globin gene, the HbS allele. SCT offers protection against malaria, controlling parasite density and preventing progression to symptomatic malaria. However, it remains unclear whether SCT also affects transmissi...

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Detalles Bibliográficos
Autores principales: Ngou, Christelle M., Bayibéki, Albert N., Abate, Luc, Makinde, Olesula S., Feufack-Donfack, Lionel B., Sarah-Matio, Elangwe M., Bouopda-Tuedom, Aline G., Taconet, Paul, Moiroux, Nicolas, Awono-Ambéné, Parfait H., Talman, Arthur, Ayong, Lawrence S., Berry, Antoine, Nsango, Sandrine E., Morlais, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173526/
https://www.ncbi.nlm.nih.gov/pubmed/37165325
http://dx.doi.org/10.1186/s12879-023-08134-x