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Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition
BACKGROUND: Prostate Cancer (PCa) represents one of the most commonly diagnosed neoplasms in men and is associated with significant morbidity and mortality. Therapy resistance and significant side effects of current treatment strategies indicate the need for more effective agents to treat both andro...
Autores principales: | Saha, Achinto, Zhao, Shengyuan, Kindall, Austin, Wilder, Carly, Friedman, Chelsea A., Clark, Rachel, Georgiou, George, Stone, Everett, Kidane, Dawit, DiGiovanni, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173527/ https://www.ncbi.nlm.nih.gov/pubmed/37170264 http://dx.doi.org/10.1186/s13046-023-02677-2 |
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