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Glucocorticoid Receptor (GR) antagonism as disease-modifying treatment for MDD with childhood trauma: protocol of the RESET-medication randomized controlled trial

BACKGROUND: Major depressive disorder (MDD) is a heterogeneous psychiatric disorder. Childhood trauma (CT, emotional/physical/sexual abuse or neglect before the age of 18) is one of the largest and most consistent risk factors for development and poor course of MDD. Overactivity of the HPA-axis and...

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Detalles Bibliográficos
Autores principales:	Linsen, F., Broeder, C., Sep, M. S. C., Verhoeven, J. E., Bet, P. M., Penninx, B. W. J. H., Meijer, O. C., Vinkers, C. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173560/ https://www.ncbi.nlm.nih.gov/pubmed/37170109 http://dx.doi.org/10.1186/s12888-023-04830-9

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