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MALAT1 functions as a transcriptional promoter of MALAT1::GLI1 fusion for truncated GLI1 protein expression in cancer

BACKGROUND: The long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a cancer biomarker. Furthermore, fusion of the MALAT1 gene with glioma-associated oncogene 1 (GLI1) is a diagnostic marker of plexiform fibromyxoma and gastroblastoma; however, the function of this...

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Detalles Bibliográficos
Autores principales: Hamada, Taiji, Higashi, Michiyo, Yokoyama, Seiya, Akahane, Toshiaki, Hisaoka, Masanori, Noguchi, Hirotsugu, Furukawa, Tatsuhiko, Tanimoto, Akihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173563/
https://www.ncbi.nlm.nih.gov/pubmed/37165307
http://dx.doi.org/10.1186/s12885-023-10867-6