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Loss of CpG island immunity to DNA methylation induced by mutation

The inheritance of acquired traits in mammals is a highly controversial topic in biology. Recently, Takahashi et al. (Cell 186:715–731, 2023) have reported that insertion of CpG-free DNA into a CpG island (CGI) can induce DNA methylation of the CGI and that this aberrant methylation pattern can be t...

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Detalles Bibliográficos
Autores principales:	Horsthemke, Bernhard, Bird, Adrian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Comment
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173581/ https://www.ncbi.nlm.nih.gov/pubmed/37170330 http://dx.doi.org/10.1186/s13072-023-00488-5

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