Tandem detergent-extraction and immunoprecipitation of proteinopathy: Scalable enrichment of ALS-associated TDP-43 aggregates

Transactive response DNA-binding protein of 43 kDa (TDP-43) is a highly conserved, ubiquitously expressed nucleic acid-binding protein that regulates DNA/RNA metabolism. Genetics and neuropathology studies have linked TDP-43 to several neuromuscular and neurological disorders including amyotrophic l...

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Detalles Bibliográficos
Autores principales: Evangelista, Baggio A., Cahalan, Shannon R., Ragusa, Joey V., Mordant, Angie, Necarsulmer, Julie C., Perna, Robert J., Ajit, Tejazaditya, White, Kristen, Barker, Natalie K., Tian, Xu, Cohen, Sarah, Meeker, Rick, Herring, Laura E., Cohen, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173608/
https://www.ncbi.nlm.nih.gov/pubmed/37182104
http://dx.doi.org/10.1016/j.isci.2023.106645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173608/
https://www.ncbi.nlm.nih.gov/pubmed/37182104
http://dx.doi.org/10.1016/j.isci.2023.106645

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