Cargando…

α‐Synuclein decoy peptide protects mice against α‐synuclein‐induced memory loss

AIMS: We previously found that a decoy peptide derived from the C‐terminal sequence of α‐Synuclein (αSyn) prevents cytotoxic αSyn aggregation caused by fatty acid‐binding protein 3 (FABP3) in vitro. In this study, we continued to utilize αSyn‐derived peptides to further validate their effects on αSy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Qingyun, Kawahata, Ichiro, Jia, Wenbin, Wang, Haoyang, Cheng, An, Yabuki, Yasushi, Shioda, Norifumi, Fukunaga, Kohji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173724/ https://www.ncbi.nlm.nih.gov/pubmed/36786129 http://dx.doi.org/10.1111/cns.14120

Ejemplares similares

An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3
por: Fukui, Naoya, et al.
Publicado: (2021)

Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain
por: Yabuki, Yasushi, et al.
Publicado: (2020)

Pathogenic Impact of α-Synuclein Phosphorylation and Its Kinases in α-Synucleinopathies
por: Kawahata, Ichiro, et al.
Publicado: (2022)

Impact of Fatty Acid-Binding Proteins in α-Synuclein-Induced Mitochondrial Injury in Synucleinopathy
por: Cheng, An, et al.
Publicado: (2021)

Dopamine D2 Long Receptors Are Critical for Caveolae-Mediated α-Synuclein Uptake in Cultured Dopaminergic Neurons
por: Kawahata, Ichiro, et al.
Publicado: (2021)

Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP(+)-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons
por: Kawahata, Ichiro, et al.
Publicado: (2019)

Anti-Epileptic Effects of FABP3 Ligand MF1 through the Benzodiazepine Recognition Site of the GABA(A) Receptor
por: Yabuki, Yasushi, et al.
Publicado: (2020)

Fatty Acid-Binding Proteins: Their Roles in Ischemic Stroke and Potential as Drug Targets
por: Guo, Qingyun, et al.
Publicado: (2022)

Epidermal Fatty Acid-Binding Protein 5 (FABP5) Involvement in Alpha-Synuclein-Induced Mitochondrial Injury under Oxidative Stress
por: Wang, Yifei, et al.
Publicado: (2021)

α-Synuclein liquid condensates fuel fibrillar α-synuclein growth
por: Piroska, Leonard, et al.
Publicado: (2023)

Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity
por: Ysselstein, Daniel, et al.
Publicado: (2017)

Binding Stability of Antibody—α-Synuclein Complexes Predicts the Protective Efficacy of Anti-α-synuclein Antibodies
por: Höllerhage, Matthias, et al.
Publicado: (2022)

Acetylated α-Tubulin and α-Synuclein: Physiological Interplay and Contribution to α-Synuclein Oligomerization
por: Calogero, Alessandra Maria, et al.
Publicado: (2023)

Partial Peptide of α-Synuclein Modified with Small-Molecule Inhibitors Specifically Inhibits Amyloid Fibrillation of α-Synuclein
por: Yoshida, Wataru, et al.
Publicado: (2013)

α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation
por: Falke, Marcel, et al.
Publicado: (2019)

Spermidine protects against α-synuclein neurotoxicity
por: Büttner, Sabrina, et al.
Publicado: (2014)

Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons
por: Guo, Qingyun, et al.
Publicado: (2022)

Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein
por: Sacino, Amanda N, et al.
Publicado: (2013)

α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
por: Tran, Hien T., et al.
Publicado: (2014)

Inducing α-synuclein compaction: a new strategy for inhibiting α-synuclein aggregation?
por: Pinheiro, Francisca, et al.
Publicado: (2019)

The Aggregation of Huntingtin and α-Synuclein
por: Chánez-Cárdenas, María Elena, et al.
Publicado: (2012)

Modulating the Amyloidogenesis of α-Synuclein
por: Sivanesam, Kalkena, et al.
Publicado: (2016)

Functionalization of α-synuclein fibrils
por: Povilonienė, Simona, et al.
Publicado: (2015)

Versatile Structures of α-Synuclein
por: Wang, Chuchu, et al.
Publicado: (2016)

The Synaptic Function of α-Synuclein
por: Burré, Jacqueline
Publicado: (2015)

Proteasome impairment by α-synuclein
por: Zondler, Lisa, et al.
Publicado: (2017)

Alternative Structures of α-Synuclein
por: Dułak, Dawid, et al.
Publicado: (2020)

Monitoring α-synuclein aggregation
por: Estaun-Panzano, Juan, et al.
Publicado: (2023)

Dopamine-Mediated Oxidation of Methionine 127 in α-Synuclein Causes Cytotoxicity and Oligomerization of α-Synuclein
por: Nakaso, Kazuhiro, et al.
Publicado: (2013)

Salivary total α-synuclein, oligomeric α-synuclein and SNCA variants in Parkinson’s disease patients
por: Kang, Wenyan, et al.
Publicado: (2016)

Pink1 interacts with α-synuclein and abrogates α-synuclein-induced neurotoxicity by activating autophagy
por: Liu, Jia, et al.
Publicado: (2017)

The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons
por: Anderson, Eric N., et al.
Publicado: (2020)

α-Synuclein fibril-specific nanobody reduces prion-like α-synuclein spreading in mice
por: Butler, Yemima R., et al.
Publicado: (2022)

Monitoring α-synuclein Aggregation Induced by Preformed α-synuclein Fibrils in an In Vitro Model System
por: Kim, Beom Jin, et al.
Publicado: (2023)

Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
por: Thomas, Bobby, et al.
Publicado: (2011)

Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins
por: Carnazza, Kathryn E., et al.
Publicado: (2022)

T cells of Parkinson’s disease patients recognize α–synuclein peptides
por: Sulzer, David, et al.
Publicado: (2017)

Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions
por: Tóth, Gergely, et al.
Publicado: (2019)

Correction: Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
por: Thomas, Bobby, et al.
Publicado: (2012)

Low CSF Levels of Both α-Synuclein and the α-Synuclein Cleaving Enzyme Neurosin in Patients with Synucleinopathy
por: Wennström, Malin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_185u029sdal2hchue571173184