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Dexmedetomidine enables copper homeostasis in cerebral ischemia/reperfusion via ferredoxin 1

Excessive oxygen free radicals and toxic substances are generated in cerebral ischemia-reperfusion (I/R) process. Dexmedetomidine (DEX), a common anesthetic and sedative drug, can considerably boost glutathione (GSH), which has anti-copper influx effects. Focusing on cuproptosis, the mechanism of DE...

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Detalles Bibliográficos
Autores principales:	Guo, Qingduo, Ma, Meina, Yu, Hong, Han, Yuepeng, Zhang, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173798/ https://www.ncbi.nlm.nih.gov/pubmed/37162502 http://dx.doi.org/10.1080/07853890.2023.2209735

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