Hepatic nuclear factor 4 alpha promotes the ferroptosis of lung adenocarcinoma via transcriptional activation of cytochrome P450 oxidoreductase

BACKGROUND: Lung adenocarcinoma is one of the most prevalent cancers while ferroptosis is crucial for cancer therapies. This study aims to investigate the function and mechanism of hepatic nuclear factor 4 alpha (HNF4A) in lung adenocarcinomas’ ferroptosis. MATERIALS AND METHODS: HNF4A expression in...

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Detalles Bibliográficos
Autores principales: Besskaya, Valeria, Zhang, Huan, Bian, Yunyi, Liang, Jiaqi, Bi, Guoshu, Shan, Guangyao, Zhan, Cheng, Lin, Zongwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174064/
https://www.ncbi.nlm.nih.gov/pubmed/37180584
http://dx.doi.org/10.7717/peerj.15377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174064/
https://www.ncbi.nlm.nih.gov/pubmed/37180584
http://dx.doi.org/10.7717/peerj.15377

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