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Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2

Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a significant public health burden with limited treatment options. Many β-coronaviruses, including SARS-CoV-2, gain entry to host cells through the interaction of SARS-CoV-2 spike protein...

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Detalles Bibliográficos
Autores principales: Bednash, Joseph S., Johns, Finny, Farkas, Daniela, Elhance, Ajit, Adair, Jessica, Cress, Kirstin, Yount, Jacob S., Kenney, Adam D., Londino, James D., Mallampalli, Rama K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174169/
https://www.ncbi.nlm.nih.gov/pubmed/36730646
http://dx.doi.org/10.1165/rcmb.2022-0331OC

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