Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding

Chronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use...

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Autores principales: Fistrek Prlic, Margareta, Jelakovic, Mislav, Brinar, Marko, Grgic, Dora, Romic, Ivan, Marusic, Zlatko, Ivandic, Ema, Jelakovic, Bojan, Vukovic Brinar, Ivana, Krznaric, Zeljko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174228/
https://www.ncbi.nlm.nih.gov/pubmed/37181355
http://dx.doi.org/10.3389/fmed.2023.1097469
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author Fistrek Prlic, Margareta
Jelakovic, Mislav
Brinar, Marko
Grgic, Dora
Romic, Ivan
Marusic, Zlatko
Ivandic, Ema
Jelakovic, Bojan
Vukovic Brinar, Ivana
Krznaric, Zeljko
author_facet Fistrek Prlic, Margareta
Jelakovic, Mislav
Brinar, Marko
Grgic, Dora
Romic, Ivan
Marusic, Zlatko
Ivandic, Ema
Jelakovic, Bojan
Vukovic Brinar, Ivana
Krznaric, Zeljko
author_sort Fistrek Prlic, Margareta
collection PubMed
description Chronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use is a documented adverse effect but is underrecognized as a cause of gastrointestinal symptoms in patients with CKD. We report a case of a 74-year-old woman taking low-dose sevelamer with serious gastrointestinal adverse effects causing colon rupture and severe gastrointestinal bleeding.
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spelling pubmed-101742282023-05-12 Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding Fistrek Prlic, Margareta Jelakovic, Mislav Brinar, Marko Grgic, Dora Romic, Ivan Marusic, Zlatko Ivandic, Ema Jelakovic, Bojan Vukovic Brinar, Ivana Krznaric, Zeljko Front Med (Lausanne) Medicine Chronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use is a documented adverse effect but is underrecognized as a cause of gastrointestinal symptoms in patients with CKD. We report a case of a 74-year-old woman taking low-dose sevelamer with serious gastrointestinal adverse effects causing colon rupture and severe gastrointestinal bleeding. Frontiers Media S.A. 2023-04-27 /pmc/articles/PMC10174228/ /pubmed/37181355 http://dx.doi.org/10.3389/fmed.2023.1097469 Text en Copyright © 2023 Fistrek Prlic, Jelakovic, Brinar, Grgic, Romic, Marusic, Ivandic, Jelakovic, Vukovic Brinar and Krznaric. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Fistrek Prlic, Margareta
Jelakovic, Mislav
Brinar, Marko
Grgic, Dora
Romic, Ivan
Marusic, Zlatko
Ivandic, Ema
Jelakovic, Bojan
Vukovic Brinar, Ivana
Krznaric, Zeljko
Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
title Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
title_full Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
title_fullStr Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
title_full_unstemmed Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
title_short Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
title_sort case report: sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174228/
https://www.ncbi.nlm.nih.gov/pubmed/37181355
http://dx.doi.org/10.3389/fmed.2023.1097469
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