Nimodipine augments cerebrovascular reactivity in aging but runs the risk of local perfusion reduction in acute cerebral ischemia

INTRODUCTION: The efficacy of cerebrovascular reactivity (CVR) is taken as an indicator of cerebrovascular health. METHODS AND RESULTS: We found that CVR tested with the inhalation of 10 % CO(2) declined in the parietal cortex of 18-20-month-old rats. The CVR deficit in old rats was coincident with...

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Detalles Bibliográficos
Autores principales: Kecskés, Szilvia, Menyhárt, Ákos, Bari, Ferenc, Farkas, Eszter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174256/
https://www.ncbi.nlm.nih.gov/pubmed/37181624
http://dx.doi.org/10.3389/fnagi.2023.1175281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174256/
https://www.ncbi.nlm.nih.gov/pubmed/37181624
http://dx.doi.org/10.3389/fnagi.2023.1175281

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