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Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis

This article highlights a clinical case of successful treatment of a 79-year-old multimorbid patient with a hip fracture resulting from a household injury. On the first day, the patient’s injury was complicated by infection and pneumonia. As a result, arterial hypotension, tachysystole, and respirat...

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Autores principales: Kadralinova, Assiya, Bekniyazova, Assema Zh., Konkayeva, Maiya E., Yeltayeva, Aigerim A., Konkayev, Aidos K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174454/
https://www.ncbi.nlm.nih.gov/pubmed/37181364
http://dx.doi.org/10.3389/fmed.2023.1148555
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author Kadralinova, Assiya
Bekniyazova, Assema Zh.
Konkayeva, Maiya E.
Yeltayeva, Aigerim A.
Konkayev, Aidos K.
author_facet Kadralinova, Assiya
Bekniyazova, Assema Zh.
Konkayeva, Maiya E.
Yeltayeva, Aigerim A.
Konkayev, Aidos K.
author_sort Kadralinova, Assiya
collection PubMed
description This article highlights a clinical case of successful treatment of a 79-year-old multimorbid patient with a hip fracture resulting from a household injury. On the first day, the patient’s injury was complicated by infection and pneumonia. As a result, arterial hypotension, tachysystole, and respiratory failure progressed. With manifestations of sepsis, the patient was transferred to the intensive care unit. Surgical treatment in such a situation was contraindicated due to the high operational and anesthesiological risks, the unstable severe condition of the patient, as well as the presence of concomitant pathology in the form of coronary heart disease, obesity, and schizophrenia. According to the new sepsis management guideline, it was decided to use a continuous 24-h infusion of meropenem in addition to the complex treatment of sepsis. The use of continuous infusion of meropenem in this clinical situation may have caused the patient’s clinical improvement, which increased her quality of life and decreased the length of ICU stay and total hospital stay, despite an unfavorable cumulative prognosis and a high risk of in-hospital mortality.
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spelling pubmed-101744542023-05-12 Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis Kadralinova, Assiya Bekniyazova, Assema Zh. Konkayeva, Maiya E. Yeltayeva, Aigerim A. Konkayev, Aidos K. Front Med (Lausanne) Medicine This article highlights a clinical case of successful treatment of a 79-year-old multimorbid patient with a hip fracture resulting from a household injury. On the first day, the patient’s injury was complicated by infection and pneumonia. As a result, arterial hypotension, tachysystole, and respiratory failure progressed. With manifestations of sepsis, the patient was transferred to the intensive care unit. Surgical treatment in such a situation was contraindicated due to the high operational and anesthesiological risks, the unstable severe condition of the patient, as well as the presence of concomitant pathology in the form of coronary heart disease, obesity, and schizophrenia. According to the new sepsis management guideline, it was decided to use a continuous 24-h infusion of meropenem in addition to the complex treatment of sepsis. The use of continuous infusion of meropenem in this clinical situation may have caused the patient’s clinical improvement, which increased her quality of life and decreased the length of ICU stay and total hospital stay, despite an unfavorable cumulative prognosis and a high risk of in-hospital mortality. Frontiers Media S.A. 2023-04-27 /pmc/articles/PMC10174454/ /pubmed/37181364 http://dx.doi.org/10.3389/fmed.2023.1148555 Text en Copyright © 2023 Kadralinova, Bekniyazova, Konkayeva, Yeltayeva and Konkayev. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Kadralinova, Assiya
Bekniyazova, Assema Zh.
Konkayeva, Maiya E.
Yeltayeva, Aigerim A.
Konkayev, Aidos K.
Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_full Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_fullStr Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_full_unstemmed Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_short Case report: Successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
title_sort case report: successful experience using continuous infusion of meropenem in a geriatric patient with hip fracture complicated by sepsis
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174454/
https://www.ncbi.nlm.nih.gov/pubmed/37181364
http://dx.doi.org/10.3389/fmed.2023.1148555
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