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Improving retinal vascular endothelial cell tropism through rational rAAV capsid design

Vascular endothelial cells (VEC) are essential for retinal homeostasis and their dysfunction underlies pathogenesis in diabetic retinopathy (DR) and exudative age-related macular degeneration (AMD). Studies have shown that recombinant adeno-associated virus (rAAV) vectors are effective at delivering...

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Detalles Bibliográficos
Autores principales:	Periasamy, Ramesh, Patel, Dwani D., Boye, Sanford L., Boye, Shannon E., Lipinski, Daniel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174500/ https://www.ncbi.nlm.nih.gov/pubmed/37167304 http://dx.doi.org/10.1371/journal.pone.0285370

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